魚鱗膠原蛋白

CN100358432C - 鱼鳞胶原蛋白的生产方法 - Google Patents

鱼鳞胶原蛋白的生产方法 Download PDF

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Publication numberCN100358432C CN100358432C CNB200310114500XA CN200310114500A CN100358432C CN 100358432 C CN100358432 C CN 100358432C CN B200310114500X A CNB200310114500X A CN B200310114500XA CN 200310114500 A CN200310114500 A CN 200310114500A CN 100358432 C CN100358432 C CN 100358432CAuthorityCNChinaPrior art keywordsfish scalecollagenfishscale collagenremovePrior art date2003-12-16Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) ActiveApplication numberCNB200310114500XAOther languages English (en) Other versions CN1628540A (zhInventor苗强Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.) WEIHAI YUWANG GROUP MARINE BIOLOGICAL ENGINEERING CO., LTD. Original AssigneeWEIHAI YUWANG AQUATIC CO LtdPriority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)2003-12-16Filing date2003-12-16Publication date2008-01-02 2003-12-16 Application filed by WEIHAI YUWANG AQUATIC CO Ltd filed Critical WEIHAI YUWANG AQUATIC CO Ltd 2003-12-16 Priority to CNB200310114500XA priority Critical patent/CN100358432C/zh 2005-06-22 Publication of CN1628540A publication Critical patent/CN1628540A/zh 2008-01-02 Application granted granted Critical 2008-01-02 Publication of CN100358432C publication Critical patent/CN100358432C/zh Status Active legal-status Critical Current 2023-12-16 Anticipated expiration legal-status Critical

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241000251468 Actinopterygii Species 0.000 title claims abstract description 102
102000008186 Collagen Human genes 0.000 title claims abstract description 44
108010035532 Collagen Proteins 0.000 title claims abstract description 44
229960005188 collagen Drugs 0.000 title claims abstract description 44
229920001436 collagen Polymers 0.000 title claims abstract description 44
238000004519 manufacturing process Methods 0.000 title claims abstract description 12
239000007788 liquid Substances 0.000 claims abstract description 12
239000012535 impurity Substances 0.000 claims abstract description 11
238000005238 degreasing Methods 0.000 claims abstract description 10
239000002994 raw material Substances 0.000 claims abstract description 7
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VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound data:image/svg+xml;base64,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 data:image/svg+xml;base64,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 Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 8
UIIMBOGNXHQVGW-UHFFFAOYSA-M NaHCO3 Chemical compound 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210000001519 tissues Anatomy 0.000 description 1

Abstract

本发明涉及一种鱼鳞胶原蛋白的生产方法，其选用优质的鱼鳞作原料，进行前处理，去掉鱼鳞表面的粘稠物质及其他杂质，而后干燥去醒，接着采用酸碱法进行脱灰、脱脂，脱灰、脱脂后进行高压催化蒸解，提炼液体状的出低分子的蛋白肽鱼鳞胶原蛋白产品。本发明充分利用了水产资源，将鱼鳞废弃物变废为宝，既减少了对环境的污染，又从根本上保证了胶原蛋白的品质；生产工艺简单，操作性强，成本低。用其做原料，可以加工制作各种营养液和保健食品，非常利于人体吸收。

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CN100358432C - 鱼鳞胶原蛋白的生产方法 - Google Patents
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Description

鱼鳞胶原蛋白的生产方法

技术领域

本发明涉及一种食品的生产方法，具体讲是一种鱼鳞胶原蛋白的生产方法。

背景技术

我们知道，胶原产品虽被广泛应用于化妆品行业、医疗行业，但在食品行业的应用很少。迄今为止，几乎所有的胶原蛋白都是来自陆地生动物的皮和骨。但是最近由于在欧州的流行的传染性极强的疯牛病等传染病，人们对从这些陆地生动物中提取的胶原蛋白的安全性提出了质疑。在加上动物保护的霈要，胶原产品的来源受限。而鱼鳞中含有丰富的胶原蛋白，该类胶原中含有多种氨基酸，能提高人体细胞营养，促进皮肤和骨骼组织的新陈代谢，增强皮肤弹力，使皮肤润滑细腻，另外对预防骨质疏松症和风湿性关节炎、提高人体免役力、增强生命活力具有良好的作用。但鱼鳞中的营养成分一直被人们所遗忘，国内，大量的可利用的鱼鳞被当作垃圾处理，不但没有充分利用鱼鳞的价值，而且还污染环境。发明内容

本发明所要解决的技术问题是克服上述现有技术的不足，提供一种工艺简单，操作性强，成本低，可充分利用水产加工业的鱼鳞下脚料，变废为宝的鱼鳞胶原蛋白的生产方法，进而将其加工成人类可以食用的蕾养及保健食

口

本发明解决上述技术问题采用的技术方案是：一种鱼鳞胶原蛋白的生产

方法，其特征是：

a. 采用优质的鱼鳞作原料，在2%~8%的盐水中浸泡10-20分钟，搅拌、洗涤，去掉鱼鳞表面的粘稠物质及其他杂质；

b. 干燥，将鱼鳞自然晒干，直到含水量小于15%,晒干后去掉杂质及不清洁的鱼鳞，贮存备用；

c. 脱脂，将上述鱼鳞放入塑料容器中，用水浸泡，加入1~3%鱼鳞重量的碳酸氢钠，搅拌，除去鱼鳞中的脂类物质，过滤冲洗； d. 脱灰，将上述鱼鳞加入容器中，加水瀵泡，而后加入50~75%鱼解重量的稀盐酸，拨拌，直至无泡沫产生为止，脱去鱼鳞中的灰分，用水冲洗，并加入碳酸氢钠中和，将PH控制在5〜5.5;

e. 催化蒸煮，将加入适l:羟基磷灰石的水煮沸，再将上述鱼鳞放入锅内继续蒸煮，提炼出鱼SI胶原蛋白，直到鱼鳞胶原蛋白的浓度达到8〜20%时停止加热，过滤除去不溶物质；

f. 高温高压蒸解，过滤后的鱼鳞胶原蛋白溶液装入离压锅内，高温高压下蒸解2〜5小时，静置3〜8小时，过滤，得液体鱼麟胶尿蛋白产品。

本发明由于采用酸械法脱灰脱脂，高温高压催化蒸解，得到便于包装、储存，易于饮食、吸收的液体状鱼鳞胶原蛋白产品，具有固有的的色、香、味营养成分。该产品作原料可以用来加工制作各种奢养液和保健食品。具体实施方式

下面结合实施例对本发明做进一步说明。

实施例l: 一种鱼鍵胶原蛋白的生产方法，其具体步骤是：

a. 首先，选料并进行前处理，采用优质的鱼鳞作原料，鱼鱗可以是淡水鱼戒海水鱼的鱼籌，在3外的盐水中漫泡12分钟，不断攙拌，去撺鱼鱗表面的粘稠物质及其他杂质，洗涤、沥水。

b. 干燥,将上述鱼麟自然晒干，直到含水量小于15%,主要目的去掉鱼

鳞臞味、更便于贮存，晒干后去掉杂质及不淸洁的鱼鳞，贮存备用。

c. 脱脂，选出上述鱼鳞100千克（以100千克鱼鳞为例，以下同）加入塑料容器中，加水浸泡，加入1.5千克的康酸氣钠，推拌，除去鱼鑽中的脂类物质，过滤冲洗。该过程去除了鱼麟中的脂类物质。

d. 脱灰，将上述鱼鳞加入容器中，加水漫泡，而后加入50千克的稀盐酸，立即搅拌，直至无泡沫产生为止，脱去鱼解中的灰分，用水冲洗，并加入碳酸氢钠中和，将PH控制在5〜5.5。

e. 高温催化蒸煮，将加入适量羟基磷灰石的水意沸，将上述脱灰、脱簾的鱼鳞放入蒸漱锅内继续蒸煮，羟基稱灰石做催化剂，熬錄出鱼麟胶原蛋白, 用浓度计測定鱼麟胶原蛋白的浓度，可每隔十分钟一澜，直到feii胶原蛋白的浓度达到10%时停止加热，过滤，得液态大分子鱼鳞胶原蛋白，过滤，除

去不溶物质。

f.高温高压蒸解，过滤后液体装入高压锅内，高温高压下蒸解3.5小时，使胶状大分子鱼鳞胶原蛋白断链，分解成低分子的蛋白肽，最后蒸解成液体状的鱼鳞胶原蛋白产品，蒸解压力为1.1个大气压，温度为112°C,静置6 个小时后，过滤，除去杂质，得液体鱼鳞胶原蛋白产品。

实施例2: —种鱼鳞胶原蛋白的生产方法，其具体步骤是：

a. 首先，选料并进行前处理，采用优质的鱼鳞作原料，鱼鳞可以是淡水鱼或海水鱼的鱼鳞，在5%的盐水中浸泡15分钟，不断推拌，去掉鱼鱗表面的粘稠物质及其他杂质，洗涤、沥水。

b. 干燥，将上述鱼鳞自然晒干，直到含水量小于15%，主要目的去掉鱼鳞腥味、更便于贮存，晒干后去掉杂质及不清洁的鱼鳞，贮存备用。

c. 脱脂，选出上述鱼鱗100千克（以IOO千克鱼鳞为例，以下同）加入塑料容器中，加水浸泡，加入3千克的碳酸氢钠，搅拌，除去鱼鳞中的脂类物质，过滤冲洗。该过程去除了鱼鳞中的脂类物质。

d. 脱灰，将上述鱼鳞加入容器中，加水浸泡，而后加入65千克的稀盐酸，立即搅拌，直至无泡沫产生为止，脱去鱼鳞中的灰分，用水冲洗，并加入碳酸氢钠中和，将PH控制在5〜5.5。

e. 高温催化蒸煮，将加入适量羟基碟灰石的水煮沸，将上述脱灰、贜簾的鱼鳞放入蒸煮锅内继续蒸煮，羟基磷灰石做催化剂，熬炼出鱼鳞胶原蛋白，用浓度计测定鱼鱗胶原蛋白的浓度，可每隔十分钟一测，直到鱼鳞胶原蛋白的浓度达到14%时停止加热，过滤，得液态大分子鱼鳞胶原蛋白，过滤，除去不溶物质。

f.高温高压蒸解，过滤后液体装入高压锅内，高温高压下蒸解3.5小时，使胶状大分子鱼鱗胶原蛋白断链，分解成低分子的蛋白肽，最后蒸解成液体状的鱼鳞胶原蛋白产品，蒸解压力为1.2个大气压，温度为115'C，静置4 个小时后，过滤，除去杂质，得液体鱼鳞胶原蛋白产品。

本发明蒸解后的鱼鳞胶原产品，用自动装填机装入棕色玻璃瓶中，并

在120X:条件进行商濂杀菌。用其做屎料，可以加工制作各种蕾养液和«#食品。

本发明的鱼鳞胶原蛋白产品生产方法的优点在于:充分利用了水产资源, 将鱼鳞废弃物变废为宝，既减少了对环境的污染，又从根本上保证了胶原蛋白的品质；生产过程中，采甩酸碱法脱灰脱脂，有效去除了糖类和脂类成分; 高温高压催化蒸解，胶原蛋白最终被分解成低分子的蛋白肽，非常利于人体吸收；工艺简单，操作性强，成本低。

Claims (1)

1.一种鱼鳞胶原蛋白的生产方法，其特征是： a.采用优质的鱼鳞作原料，在2％～8％的盐水中浸泡10-20分钟，搅拌、洗涤，去掉鱼鳞表面的粘稠物质及其他杂质； b.干燥，将鱼鳞自然晒干，直到含水量小于15％，晒干后去掉杂质及不清洁的鱼鳞，贮存备用； c.脱脂，将上述鱼鳞放入塑料容器中，用水浸泡，加入1～3％鱼鳞重量的碳酸氢钠，搅拌，除去鱼鳞中的脂类物质，过滤冲洗； d.脱灰，将上述鱼鳞加入容器中，加水浸泡，而后加入50～75％鱼鳞重量的稀盐酸，搅拌，直至无泡沫产生为止，脱去鱼鳞中的灰分，用水冲洗，并加入碳酸氢钠中和，将PH控制在5～5.5； e.催化蒸煮，将加入羟基磷灰石的水煮沸，再将上述鱼鳞放入锅内继续蒸煮，提炼出鱼鳞胶原蛋白，直到鱼鳞胶原蛋白的浓度达到8～20％时停止加热，过滤除去不溶物质； f.高温高压蒸解，过滤后的鱼鳞胶原蛋白溶液装入高压锅内，高温高压下蒸解2～5小时，静置3～8小时，过滤，得液体鱼鳞胶原蛋白产品。

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